SARS CoV-2 (formerly known as 2019-nCoV, or "Wuhan Coronavirus") COVID-19 Outbreak
ISAR has adopted the taxonomy and nomenclature just recommended by the Coronavirus Study Group (CSG) of the International Committee on Taxonomy of Viruses. The virus is now considered a sister to the SARS virus. This group of coronaviruses has been renamed as SARS-CoVs, and the previously known as 2019-nCoV is now named SARS CoV-2.
ISAR has also adopted the disease name indicated by WHO, COVID-19 (for coronavirus disease- 2019).
With the COVID-19 (Coronavirus disease 2019) outbreak progressing so quickly since it started last December, the situation has been very dynamic and the information equally fluid. New information has become available by the hour, drastically changing the potential impact of the epidemic or incrementally increasing our understanding of the outbreak and its agent. In such a dynamic scenario, information becomes too quickly outdated or superseded as to attempt to periodically summarize it or cover it all.
As a service to the community interested in antiviral research and development, ISAR News will instead publish in this page a list of curated links to sources with verified and current information; these links will be continuously updated.
ISAR members are invited to submit any links that may be of interest for their evaluation and potential addition to this page.
We publish this page in the hope that our members, and the antiviral community at large, will find it useful in their quest for a world in which viral outbreaks are no longer a constant major threat.
ANNOUNCING AN ISAR WEBINAR ON THE PROSPECTS OF THERAPEUTICS AGAINST SARS CoV-2 AND THEIR POTENTIAL USE IN THE COVID-19 OUTBREAK - 4 PM CST Thursday, Feb 27th, 2020
Dr. Mark Denison, M.D. Director, Division of Infectious Diseases and Professor of Pathology, Microbiology & Immunology, Vanderbilt University School of Medicine, Nashville, TN
COVID-19: fighting panic with information (The Lancet Editorial)
Primary sources of official information:
All 2019-nCoV clinical trials registered and listed in "clinical trials.gov" (most are not yet recruiting)
China CDC epidemic tracking (updated daily)
Real time tracking of the epidemic by the Center for Systems Science and Engineering (CSSE), John Hopkins University
Coronavirus latest: has the outbreak in China peaked? - A commentary in Nature discussing the apparent peak and the possibility of a secondary peak around February 21 as a consequence of the return to work after the New Year Holiday
A commentary on the naming of the virus and the disease Science commentary
Are pangolins infected with the 2019-nCoV?_Nature commentary on yet unpublished research- A link to the preprint presenting the (limited) evidence under "Pre-Prints and Published papers" below.
Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (Manis javanica)-Previously published research concluding that pangolins are infected with coronaviruses
Gilead Sciences has partnered with Chinese health authorities to conduct a randomized Phase III clinical trial of remdesivir against nCoV (links to the clinical trials under "Primary Sources of Information")
Coronavirus outbreak: what’s next? _Nature magazine commentary
Mining coronavirus genomes for clues to the outbreak’s origins Science magazine commentary
The World Health Organization (WHO) and the World Economic Forum have set up a public private collaboration to provide a platform for data sharing and operational coordination, “The Pandemic Supply Chain Network (PSCN).
Aggregated scientific information sites:
Pre-prints and Published papers:
SARS-like WIV1-CoV poised for human emergence -A paper from 2016 rising the prospect of a new bat coronavirus entering the human population
The largest description of the outbreak (>44,000 cases): Vital Surveillances: The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020
Structural modeling of 2019-novel coronavirus (nCoV) spike protein reveals a proteolytically-sensitive activation loop as a distinguishing feature compared to SARS-CoV and related SARS-like coronaviruses
Genomics:Phylogeny of SARS-like betacoronaviruses
About ISAR NEWS
The official newsletter of the International Society for Antiviral Research
© Publications workgroup (Communications & Outreach Committee) and Luis M Schang, Editor